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Efficacy is important, but a treatment for a chronic condition such as schizophrenia also needs to be well tolerated so patients will stay on it over the long-term.

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Atypical antipsychotics (“second-generation” antipsychotics) include clozapine (Clozaril, generic), risperidone (Risperdal, generic), olanzapine (Zyprexa, generic), quetiapine (Seroquel), ziprasidone (Geodon), aripiprazole (Abilify), palperidone (Invega), iloperidone (Fanapt), asenapine (Saphris), and lurasidone (Latuda).

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