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What happens if insulin is taken orally? Insulin currently cannot be taken by mouth because the digestive juices in your stomach and intestine will break down the insulin before it has a chance to get into your bloodstream to do its job. If you have type 2 diabetes, you may or may not have to take insulin injections, depending on a variety of factors.
What are the warning signs of prediabetes? Classic signs and symptoms that suggest you've moved from prediabetes to type 2 diabetes include: Increased thirst. Frequent urination. Fatigue. Blurred vision.
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Is linagliptin safe in renal failure? Therefore, it can be used in normal kidney function as well as in all stages of chronic kidney disease to stage 5 (glomerular filtration rate <15 ml/min/1.73 m 2) without dose adjustments. Linagliptin was noninferior to metformin and sulfonylureas in clinical studies.

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