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In addition, AIH-PBC overlap appears to be less responsive to treatment compared to AIH alone, although this did not seem to affect survival.

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Phase I Clinical Trial of Smad7 Knockdown Using Antisense Oligonucleotide in Patients With Active Crohn's Disease.

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The use of Azathioprine Tablets USP with these agents cannot be recommended.

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Pneumocystis pneumonia has an annual incidence of 1% but is a potentially deadly complication of immunosuppressive therapy in patients with GPA, especially with prolonged lymphocytopenia.

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Azathioprine suppresses the immune system by interfering with the metabolism of immune and antibody-producing cells (lymphocytes).

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Patients who were unable to tolerate the target dose or whose weight was below 50 kg remained in the study if they tolerated a minimum dose of either 1 g of mycophenolate mofetil per day or 50 mg of azathioprine per day.

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Meier curves of the probability of remaining free of relapse were plotted for each treatment group, censored at death if it occurred before a relapse, and compared by means of a marginal Cox model stratified by disease type (newly diagnosed vs.
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