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Kearon C, Gent M, Hirsh J, Weitz J, Kovacs MJ, Anderson DR, Turpie AG, Green D, Ginsberg JS, Wells P, MacKinnon B, Julian J "A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism.

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It takes several days for warfarin to reach the therapeutic effect since the circulating coagulation factors are not affected by the drug (thrombin has a half-life time of days).

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Just to re-emphasize, you should NOT try to avoid vitamin K containing foods; rather you should maintain a consistent (week-to-week) intake in your diet -- consistency is the key!

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Likewise, a reduction of vitamin K intake following stabilization of anticoagulant therapy may result in elevation of the INR and bleeding complications.

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When a "hang time" or "infusion time" for IV thrombolytic is documented in the medical record, select "Yes".

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