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Is Wellbutrin an MAOI? Bupropion inhibits the reuptake of dopamine and norepinephrine. Studies in animals demonstrate that the acute toxicity of bupropion is enhanced by the MAO inhibitor phenelzine. At least 14 days should elapse between discontinuation of an MAOI intended to treat depression and initiation of treatment with Wellbutrin.
Does emsam cause weight gain? Of the three MAOIs listed above, phenelzine is the most likely to result in weight gain, according to a 1988 review. However, a newer formulation of an MAOI known as selegiline (Emsam) has been shown to result in weight loss during treatment. Emsam is a transdermal medication that's applied to the skin with a patch.
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